Start here for trusted, evidence-aligned options to ease infant colic, gas, and digestive discomfort. This guide highlights five product picks that address different baby needs—from gas relief to probiotics—so you can choose what’s best for your newborn or infant. Ideal for parents seeking safe, straightforward solutions and clear usage guidance.
Summary of selected products
| Product | Best For | Why It Stands Out |
|---|---|---|
| MYLICON Infants Gas Relief Drops (1 oz) | Newborns with gas and mild tummy discomfort | #1 pediatrician-recommended brand; gentle, fast-acting gas relief |
| Little Remedies Newborn Gas Relief Drops (1 oz) | Newborns with gas and tummy pain | Natural berry flavor; no artificial flavors/dyes; quick relief |
| BioGaia Protectis Baby Probiotic Drops (5 mL) | Colic, gas, fussiness from gut flora | Well-studied probiotic; safe from birth; supports digestion |
| Mommy’s Bliss Gripe Water Original (4 oz) | General gas/colic relief via herbal blend | Bestseller; gentle formulation for tummy trouble |
| Culturelle Baby Digestive Calm & Comfort Drops (8.5 mL) | Digestive upset, occasional colic | Clinically studied probiotic strains; easy daily use |
MYLICON Infants Gas Relief Drops for Infants and Babies

Features: Mylicon, the #1 pediatrician recommended brand, provides safe, effective relief of infant gas. It works gently to speed up a baby’s natural process of getting rid of gas, relieving pressure and discomfort. Safe for use with all infants—from newborns up to 12 doses per day as directed.
Best For: Parents seeking fast, doctor-endorsed relief for infant gas across feeding times. It’s a staple for newborns who experience gas after feeding or swallowing air.
Limitations: Use only as directed; avoid exceeding recommended doses, especially in very young infants.
Little Remedies Newborn Gas Relief Drops

Features: Relieves tummy pain from excess gas, no artificial flavors or dyes, natural berry flavor. Quick-acting and alcohol-free with no artificial colors or preservatives.
Best For: Families wanting a dye-free, lightly flavored option for newborn gas relief with simple ingredient rules.
Limitations: Flavor may be noticeable to some babies; note flavor is natural berry, not a strong taste profile for all infants.
Boiron Camilia Tummy for Colic

Features: Gentle homeopathic drops made with chamomile and other non-GMO ingredients. Easy, mess-free oral doses in sterile liquid form; no refrigeration required. Suitable for babies 1 month and older, with no known interactions with other medications.
Best For: Parents seeking a non-dye, non-sedative option for colic and gas relief that is easy to administer without measuring.
Limitations: Homeopathic options vary in effectiveness by infant; results can differ between babies.
BioGaia Protectis Baby Probiotic Drops

Features: Probiotic drops designed to ease crying, fussing, colic, and gas. Safe for newborns; supports digestion naturally. No dairy, soy, or gluten in this formulation.
Best For: Parents considering daily probiotic support to help with gut health and colic symptoms in newborns and young infants.
Limitations: Probiotic effects vary; consistency and timing of dosing can influence results.
Mommy’s Bliss Gripe Water Original

Features: Herbal remedy designed to ease infant gas and colic. Marketed as a gentle, trusted option for tummy trouble that can help both baby and parents rest.
Best For: Families preferring a traditional gripe water approach for general gas relief and fussiness.
Limitations: Efficacy depends on individual baby response; monitor for any sensitivities or reactions to herbal ingredients.
Buying Guide
What should I look for when choosing drops or probiotics for colic?
- Age applicability: Some products are labeled for newborns, others require a month or older. Check labeling before use.
- Active ingredients: Probiotics (specific strains) vs. gas-relief formulas vs. homeopathic options. Pick based on your baby’s symptoms and pediatrician guidance.
- Flavor and administration: Some products are flavored, others are tasteless or odorless. Consider ease of dosing and your baby’s acceptance.
- Safety and dosing: Follow directed usage. For newborns, use products designed for that age range and watch for any adverse reactions.
- Allergens and additives: If your baby has sensitivities, prefer dye-free, artificial flavor-free, or dairy-free formulations.
How to choose between probiotic drops and gas-relief drops?
- Gas-relief drops (like MYLICON or Little Remedies) target immediate discomfort from gas and air swallowing. They typically do not affect gut flora long-term.
- Probiotic drops (BioGaia, Mommy’s Bliss probiotic, Culturelle) aim to support gut health over time and may reduce recurring colic symptoms for some babies.
- Combination approach: Some families use a probiotic daily and a gas-relief drop as needed for acute discomfort, after consulting a pediatrician.
Safety and usage considerations
- Always read the product label and directions for age and dosing limits. Do not exceed recommended amounts.
- Introduce one product at a time to identify what helps your baby best without overlapping active ingredients.
- Consult a pediatrician if symptoms persist beyond a few days, or if your baby has a fever, diarrhea, or vomiting.
What about non-medicated comfort strategies?
- Burping during and after feeds to minimize swallowed air.
- Gentle tummy massage or warm (not hot) compresses to ease tension.
- Consistent feeding positions and paced bottle feeding to reduce air intake.
Comparison snapshot
- Fast-acting gas relief: MYLICON Infants Gas Relief Drops.
- Newborn-safe, dye-free option: Little Remedies Newborn Gas Relief Drops.
- Probiotic support from birth: BioGaia Protectis Drops or Culturelle Baby Digestive Calm & Comfort.
- Herbal option: Mommy’s Bliss Gripe Water Original.
- Non-prescription, easy dosing: Boiron Camilia Tummy for Colic (homeopathic).
Frequently asked questions
- Are these drops safe for newborns? Most products listed are designed for newborns or very young infants; always verify age guidelines on the product label and consult a pediatrician if unsure.
- Can I use more than one product at the same time? It’s best to introduce one product at a time to monitor effects and avoid potential interactions. Consult a pediatrician before combining products.
- Do probiotics prevent colic? Probiotics may help reduce certain digestive discomfort for some babies, but results vary and are not guaranteed for all infants.
- How quickly do gas-relief drops work? Gas-relief formulations often show effects within minutes to hours, depending on feeding patterns and individual baby physiology.
- Is flavor important for drops? Some babies respond better to flavored formulas, while others do well with unflavored options. Choose based on your baby’s acceptance and tolerance.
- Should I refrigerate any of these products? Most probiotic drops do not require refrigeration unless stated; Always follow the product’s storage guidance.